Melev 20mg Tablet

✔️ Uses of Melev 20mg Tablet

• Depression
• Obsessive-compulsive disorder
• Post-traumatic stress disorder
• Panic disorder
• Anxiety

✔️ Side Effects of Melev 20mg Tablet

• Nausea
• Tremor
• Confusion
• Dizziness
• Dry mouth
• Erectile dysfunction
• Fatigue
• Increased sweating
• Insomnia
• Loss of appetite
• Nervousness
• Sleepiness
• Delayed ejaculation
• Low sexual desire

✔️ How does Melev 20mg Tablet work?

• Melev 20 is a selective serotonin reuptake inhibitor (SSRI) antidepressant.
• It increases the levels of serotonin in the brain, improving mood and relieving physical symptoms of depression and related disorders.

✔️ Quick Suggestions:

• Maintain a balanced diet and engage in regular exercise to improve overall health and well-being. This can also boost self-esteem.
• Attend therapy sessions regularly to address underlying issues and learn coping strategies.
• Practice meditation and yoga to reduce stress and promote relaxation.
• Establish a regular sleep pattern to ensure adequate and restful sleep.
• Include foods rich in omega-3 fatty acids, amino acids, and complex carbohydrates to support neurotransmitter function and mood regulation.
• Engage in physical activity to stimulate the production of natural antidepressants, reduce stress, and improve mood.
• Refrain from smoking and limit alcohol consumption, as they can exacerbate symptoms of depression and anxiety.
• Learn about your condition, understand the treatment plan recommended by your doctor, and adhere to it diligently.
• Close monitoring is advised for individuals taking Paroxetine, especially regarding suicidal thoughts or behaviors. Promptly inform your doctor if you experience such thoughts.

✔️ Indication of Melev 20mg Tablet

Paroxetine is a medicine that belongs to the selective serotonin reuptake inhibitors (SSRI) group. It is used for the treatment of depression, obsessive-compulsive disorder (OCD), panic disorder, and other anxiety disorders.

✔️ Pharmacology

Paroxetine, the active ingredient in medications like Melev 20, is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Its efficacy is presumed to be associated with the potentiation of serotonergic activity in the central nervous system. This occurs through the inhibition of the neuronal reuptake of serotonin (5-hydroxy-tryptamine, 5-HT).

Clinical studies in humans at relevant doses have shown that paroxetine blocks the uptake of serotonin into human platelets. Additionally, in vitro studies in animals suggest that paroxetine is a potent and highly selective inhibitor of neuronal serotonin reuptake. Importantly, it has minimal effects on the reuptake of other neurotransmitters such as norepinephrine and dopamine.

In vitro radioligand binding studies have revealed that paroxetine has little affinity for various receptors, including muscarinic, alpha1, alpha2, beta-adrenergic, dopamine (D2), 5-HT1, 5-HT2, and histamine (H1) receptors. This indicates that paroxetine's therapeutic effects are primarily mediated through its action on serotonin reuptake inhibition rather than direct interaction with these receptors.

✔️ Dosage & Administration of Melev 20mg Tablet

• For depression, anxiety, and post-traumatic stress disorder: Initial dose of 20 mg daily, which may be gradually increased up to a maximum of 50 mg/day.
• For obsessive-compulsive disorder and social anxiety disorder: Initial dose of 20 mg daily, with gradual increases in 10-mg increments.
• For panic disorder: Initial dose of 10 mg daily, with weekly increases in 10-mg increments according to clinical response, up to a maintenance dose of 40-60 mg daily.
• Elderly patients and those with hepatic impairment: Start with a lower initial dose of 10 mg daily, with adjustments made cautiously.
• Take Melev 20 as advised by your doctor, with or without food, at a fixed time each day.
• Swallow the tablet whole; do not chew, crush, or break it.

✔️ Interaction

• Melev 20 may interact with other antidepressants, MAO inhibitors, and various other medications, affecting their levels and effects.
• Inform your doctor about all medications you are taking to ensure safety.

✔️ Contraindications

Concomitant use in patients taking either monoamine oxidase inhibitors (MAOIs) or thioridazine is contraindicated. This is contraindicated in patients with a hypersensitivity to Paroxetine.

✔️ Pregnancy & Lactation

Regarding labor and delivery, the specific effects of Paroxetine on these processes in humans are not well understood or documented. Further research may be needed to fully understand any potential effects.

For nursing mothers, it's important to exercise caution when taking Paroxetine because, like many other drugs, it is excreted in human breast milk. Healthcare providers should carefully consider the potential risks to the infant when deciding whether to administer Paroxetine to a breastfeeding woman. Open communication between the healthcare provider and the nursing mother is essential to make an informed decision that considers both the maternal health needs and the well-being of the infant.

✔️ Precautions:

• Inform your doctor about any medical conditions you have, including epilepsy, diabetes, liver or kidney disease, heart problems, or glaucoma.
• Pregnant or breastfeeding women should consult their doctor before taking Melev 20.
• Avoid abrupt withdrawal, as it may cause withdrawal symptoms such as upset stomach, flu-like symptoms, and sleep disturbances.
• Alcohol consumption should be avoided, as it may increase drowsiness and calmness.

✔️ Storage Conditions:

• Keep Melev 20mg Tablet out of reach of children
• Store at room temperature